Plain meaning
Start with the shortest useful explanation before going deeper.
The number of transactions a blockchain can process per second. Theoretical TPS is often much higher than sustained real-world performance. Bitcoin: ~7 TPS, Ethereum: ~15-30 TPS, Solana: ~2,000-5,000 non-vote TPS sustained (65,000 theoretical). Throughput depends on block size, block time, transaction size, and execution parallelism.