Plain meaning
Start with the shortest useful explanation before going deeper.
Loan-to-Value ratio—the percentage of collateral value that can be borrowed. Each lending protocol sets max LTV per asset (e.g., 75% for SOL means $100 SOL collateral = max $75 borrow). If debt/collateral exceeds the liquidation LTV (e.g., 85%), the position is liquidatable. Conservative LTV settings protect against rapid price drops.